Study on measuring method of thrombolyses for wire type stirrer

M. Morita, Mohammad Ajoudanian, Michiyasu Suzuki, Zhongwei Jiang
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Abstract

A cerebral thrombus or blood clot might cause cerebral stroke and even decease if the clot could not be dissolved within several hours after it was formed. This paper presents a fundamental study on development of a new type of mechanical micro stirrer for assisting the dissolution of the thrombus with a few amount of thrombolytic agent. The micro stirrer is made of a simple structure with a piezoelectric. An efficient excitation method for stirring up the thrombus to get a quick dissolution is investigated. Furthermore, to evaluate the dissolution state in vivo, the method using the stirrer as both the stimulator to beat the clot and the probe to evaluate its solubility is proposed.
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丝式搅拌器溶栓测定方法的研究
脑血栓或血凝块可能导致脑中风,如果血栓在形成后几个小时内不能溶解,甚至会导致死亡。本文对一种新型机械微搅拌器的研制进行了基础研究,以少量溶栓剂辅助溶栓。该微型搅拌器采用压电结构,结构简单。研究了一种有效的激发方法,使血栓快速溶解。此外,为了评估体内溶出状态,提出了使用搅拌器作为刺激器来打击凝块和探针来评估其溶解度的方法。
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