Novel interdigitated transducer structures for biosensoric applications

A. Bonyár, H. Santha
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引用次数: 2

Abstract

In this work we present novel interdigitated transducer (IDT) structures and their electrochemical characterization for DNA (deoxiribo-nucleic-acid) based biosensoric applications. The principle of the new structures is to maximize the so called “edge effect” of the electric field to gain faster material transfer and thus increase the performance of the biosensor. For the characterization of the gold thin film IDT structures we used electrochemical impedance spectroscopy (EIS) with three different electrode connecting regimes and single-stranded DNA monolayers. Experiments were performed to evaluate two aspects. A). The new IDT structures were evaluated based on the maximal possible signal that can be gained after hybridization of the ssDNA (single stranded) biofunctionalized electrodes and the target ssDNA chains. Results suggest that using the new electrode structures instead of the classical round shaped working electrodes is not entirely beneficial. B). In the other aspect of the experiments some electrode connecting regimes among the investigated three ones can be considered beneficial or disadvantageous in terms of sensitivity or reproducibility.
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用于生物传感应用的新型交叉式传感器结构
在这项工作中,我们提出了新的交叉式换能器(IDT)结构及其电化学表征的DNA(脱氧核糖核酸)为基础的生物传感应用。新结构的原理是最大化所谓的电场“边缘效应”,以获得更快的材料传递,从而提高生物传感器的性能。为了表征金薄膜IDT结构,我们使用了三种不同电极连接方式和单链DNA单层的电化学阻抗谱(EIS)。通过实验对两个方面进行了评价。A).根据ssDNA(单链)生物功能化电极与靶ssDNA链杂交后可获得的最大可能信号来评估新的IDT结构。结果表明,使用新的电极结构代替传统的圆形工作电极并不完全有益。B).在实验的另一方面,在所研究的三种电极连接方式中,某些电极连接方式在灵敏度或可重复性方面可以被认为是有利的或不利的。
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