Generation of Fluorescent Nanoparticles by Laser Fragmentation Technique for Electrochemiluminescent Assay

Abstract

The work describes application of semiconductor quantum dots (QDs) in electrochemiluminescent assay of amine compounds and development of new method for production of shell-free semiconductor nanoparticles using laser fragmentation technique. Two basic strategies of electroanalytical application of QDs are presented. One is based on electrode modification with polymer films containing CdSe QDs that directly participate in ECL reaction with amine coreactants. The other is based on sensitization of ECL emission from fluorescent amino acids with CdSe QDs. We have also described efficient top-down method of fluorescent CdSe nanoparticles synthesis using laser fragmentation of its powder suspension in dimethylformamide, optical properties of produced QDs and discussed the applicability of produced nanoparticles for electroanalytical techniques.