A Late Prosthetic Mitral Valve Infective Endocarditis Caused by Micrococcus spp. that Fully Recovered by Antibiotics Treatment : A Rare Case

Imam Mahbub Zam Zami, Agus Subagjo
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Abstract

Prosthetic valve endocarditis is the most severe form endocarditis with prevalence of 5.7% at 5 years and mortality with medical treatment is 26%-75%. Case Summary: Male, 46 years old, with mechanic mitral prosthetic valve >5 years, hemiparesis sinistra due to embolic stroke >4 weeks prior, was suffering from persistent fever >38,5⁰ for 2 weeks without heart failure. Three separate blood cultures came positive with Micrococcus spp. and Osler’s node was noticed. Echocardiography shown 1.0 cm x 0.9 cm vegetation at mitral prosthetic valve without paravalvular leakage. Patient was assessed as late mitral PVE. Discussion: Gentamycin, Levofloxacin, and Erythromycin were given based on susceptibility test continued by Meropenem as therapy of urinary tract infection based on susceptibility test after second blood culture result was negative. The patient underwent 42 weeks of antibiotics course. The patient was discharged with good condition, no signs and symptoms of infection or heart failure, blood test was within normal limit, no vegetations with prosthetic mitral valve functioned normally. This case shows that late PVE caused by Micrococcus spp. can be treated by 42 weeks course of antibiotics according to microbial susceptibility test.
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一例由微球菌引起的晚期假体二尖瓣感染性心内膜炎经抗生素治疗完全恢复的罕见病例
人工瓣膜心内膜炎是最严重的心内膜炎形式,5年患病率为5.7%,经药物治疗的死亡率为26%-75%。病例总结:男性,46岁,机械性二尖瓣人工瓣膜bbb50岁,4周前因栓塞性中风>引起的鼻窦炎偏瘫,持续发热>38,5⁰2周,无心力衰竭。三个单独的血培养结果为微球菌阳性,并注意到奥斯勒结。超声心动图显示人工二尖瓣1.0 cm x 0.9 cm赘生物,无瓣旁渗漏。评估患者为晚期二尖瓣PVE。讨论:第二次血培养阴性后,在药敏试验基础上给予庆大霉素、左氧氟沙星、红霉素治疗,继续给予美罗培南药敏试验治疗尿路感染。患者接受了42周的抗生素疗程。出院时病情良好,无感染及心力衰竭症状,血检正常,无赘生物,人工二尖瓣功能正常。本病例表明微球菌引起的晚期PVE可通过42周的抗生素治疗。
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