Evaluation of Family Psychoeducation Efficacy in Schizophrenia: A Way to Do it More Simply for Routinely Monitoring

Y. Hodé, A. Deruyver, Regine Vonthron, Claudine Clement, Wydad Hikmat, S. Fattah
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Abstract

Background: Despite many control trials and meta-analyses proving the positive effect and the economic interest of family psychoeducation in schizophrenia, this practice remains marginal. There may be several reasons behind the clinicians' lack of motivation to implement such programs. Simple and common evaluation tools to compare program efficacy, improve the programs' content, and guaranty the fidelity of the delivery over time by routinely monitoring the efficacy level would be a way (among many) to stimulate clinical interest in psychoeducation. Two common self-administered questionnaires used in combination, the Center for Epidemiologic Studies Depression (CESd) to assess caregivers' depressive symptoms and 20-item Life Skill Profile (LSP-20) to assess patient functioning, would be good candidates for that. Methods: Family caregivers (n = 78) of seven consecutive groups participating in a program named Profamille filled in these questionnaires before and at the end of the program and 1 year later. More than the half of the caregivers have an initial depressive score indicating a higher risk of cardiovascular mortality/morbidity. Results: Both CESd and LSP20 significantly changed 1 year later. The size effect for CESd was 1.4 and for LSP20 was 0.6. These changes were linked to a statistically significant reduction in the number of hospitalized days for the patients (by a factor 3) and a number of days lost at work for the caregivers (by a factor 4). Conclusions: These two questionnaires are therefore useful to compare different programs, obtain preliminary evidence from exploratory trials, like for the Profamille V3 program, and help ensure the fidelity of program delivery.
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精神分裂症家庭心理教育效果的评估:一种更简单的常规监测方法
背景:尽管许多对照试验和荟萃分析证明了精神分裂症家庭心理教育的积极作用和经济利益,但这种做法仍然处于边缘。在临床医生缺乏实施这些计划的动机背后,可能有几个原因。简单而通用的评估工具来比较项目的效果,改善项目的内容,并通过常规监测效果水平来保证交付的保真度,这将是激发临床对心理教育兴趣的一种方法(在许多方法中)。两种常见的自我管理问卷组合使用,抑郁症流行病学研究中心(CESd)评估照顾者的抑郁症状,20项生活技能概况(sps -20)评估病人的功能,将是很好的候选人。方法:连续7组参与Profamille项目的家庭照顾者(78名)在项目开始前、结束时及1年后分别填写问卷。超过一半的护理人员有一个最初的抑郁评分,表明心血管死亡率/发病率的风险较高。结果:1年后CESd和LSP20均有显著变化。csd的大小效应为1.4,LSP20的大小效应为0.6。这些变化与患者住院天数(因子3)和护理人员工作损失天数(因子4)的统计显著减少有关。结论:因此,这两个问卷对于比较不同的方案,从探索性试验(如Profamille V3方案)中获得初步证据有用,并有助于确保方案交付的保真度。
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