A Study of Psychiatric Comorbidity and Fear of Corona Virus in Patients with Obsessive Compulsive Disorder during Covid-19 Pandemic

Bandana Gupta, T. Bansal, Shweta Singh, A. Nischal
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Abstract

Background and objective: The WHO declared the Chinese outbreak of COVID-19 to be health risk of National and International Concern from 30th January 2020. This has significant implications on mental health , especially for patients of OCD in various ways. This study was aimed to study Psychiatric comorbidity and Fear of Corona virus in patients with obsessive-compulsive disorder (OCD) during COVID-19 pandemic and compare socio-demographic & clinical variables between patients of OCD with or without psychiatric comorbidity during COVID-19 pandemic.Methods: In person interview including 96 old and new symptomatic patients of OCD diagnosed as per ICD 10-DCR, who had onset of illness prior to COVID-19 (march 2020), between the age of 18-60 years was conducted. The disease severity was recorded on D-YBOCS, HAM-A and HAM-D. The two groups of OCD, with comorbidity and without comorbidity were compared. Fear of COVID-19 Scale was used to analyse fear of corona virus.Results: Depression was the most common psychiatric comorbidity. The fear of coronavirus in 59.4% OCD patients was observed to be mild in severity and the mean FCV-19S score to be 14.42 ± 4.19. Positive correlation was found between FCV-19S score and the YBOCS obsession subtotal score, YBOCS compulsion subtotal score, YBOCS total score, HAM-D score and HAM-A score. FCV-19S score also had a statistically significant positive correlation with D-YBOCS severity score for contamination and cleaning, severity score for hoarding and collecting, severity score for symmetry and severity score for aggression. Among the OCD patients with comorbidity, a statistically significant higher YBOCS score, D-YBOCS severity score for Contamination and Cleaning and FCV-19S score were observed when compared to OCD patients without comorbidity.Conclusions: Fear of corona virus was seen in majority of the OCD patients and was associated with increased severity of disease. The OCD patients with comorbidity had significantly higher Y-BOCS score mainly for Contamination and Cleaning.
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新冠肺炎大流行期间强迫症患者精神共病及冠状病毒恐惧的研究
背景与目的:世界卫生组织宣布自2020年1月30日起,中国新冠肺炎疫情为国家和国际关注的健康风险。这对心理健康有着重要的影响,尤其是对强迫症患者来说。本研究旨在研究COVID-19大流行期间强迫症(OCD)患者的精神共病和对冠状病毒的恐惧,并比较有或无精神共病的强迫症患者在COVID-19大流行期间的社会人口统计学和临床变量。方法:对96例按ICD 10-DCR诊断为强迫症的新老症状患者进行访谈,这些患者在2020年3月之前发病,年龄18-60岁。用D-YBOCS、HAM-A和HAM-D记录病情严重程度。比较两组强迫症患者有无合并症。对COVID-19的恐惧量表用于分析对冠状病毒的恐惧。结果:抑郁症是最常见的精神合并症。59.4%的强迫症患者对冠状病毒的恐惧程度为轻度,FCV-19S平均评分为14.42±4.19分。FCV-19S评分与YBOCS强迫症分、YBOCS强迫分、YBOCS总分、HAM-D分、HAM-A分呈显著正相关。FCV-19S评分与D-YBOCS污染和清洁严重程度评分、囤积和收集严重程度评分、对称严重程度评分和攻击严重程度评分也有统计学意义的正相关。在有合并症的强迫症患者中,与无合并症的强迫症患者相比,YBOCS评分、D-YBOCS污染和清洁严重程度评分和FCV-19S评分均有统计学意义。结论:对冠状病毒的恐惧在大多数强迫症患者中可见,并与疾病严重程度的增加有关。有合并症的强迫症患者的Y-BOCS评分显著高于对照组,主要表现在污染和清洁两项。
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