{"title":"Abortion and serological reaction of ewes after conjunctival instillation of Salmonella enterica subsp enterica ser abortusovis.","authors":"R Sanchis, P Pardon, G Abadie","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The aim of the experiment was to evaluate in pregnant ewes the clinical, bacteriological and serological effects of conjunctival instillation of S abortusovis. An individual dose of 1 x 10(10) viable S abortusovis were administered to 20 ewes 92 d after mating. Among 18 pregnant ewes, 8 aborted 110 +/- 13 d after mating, 4 had stillborn lambs and 6 a clinically normal lambing (114 +/- 1.3 d). S abortusovis was isolated from placentas, swabs and foetuses of the 12 lambings. Evolution of \"H\" agglutination titers measured by means of a microtechnique using a coloured antigen was found to be independent of the clinical results. Instillation by conjunctival route could constitute an experimental model closer to a natural mode of infection than the subcutaneous route.</p>","PeriodicalId":7914,"journal":{"name":"Annales de recherches veterinaires. Annals of veterinary research","volume":"22 1","pages":"59-64"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de recherches veterinaires. Annals of veterinary research","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The aim of the experiment was to evaluate in pregnant ewes the clinical, bacteriological and serological effects of conjunctival instillation of S abortusovis. An individual dose of 1 x 10(10) viable S abortusovis were administered to 20 ewes 92 d after mating. Among 18 pregnant ewes, 8 aborted 110 +/- 13 d after mating, 4 had stillborn lambs and 6 a clinically normal lambing (114 +/- 1.3 d). S abortusovis was isolated from placentas, swabs and foetuses of the 12 lambings. Evolution of "H" agglutination titers measured by means of a microtechnique using a coloured antigen was found to be independent of the clinical results. Instillation by conjunctival route could constitute an experimental model closer to a natural mode of infection than the subcutaneous route.