Zamtocabtagene Autoleucel (MB-CART2019.1): An Investigational CAR-T Cell Product with Tandem Targeting of CD19 and CD20 as a Potential Treatment Option for Patients with Relapsed/ Refractory B Cell Non-Hodgkin Lymphoma

Jennifer Taylor
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Abstract

Presenting at the European Hematology Association (EHA) 2022 Congress, Peter Borchmann from the University of Cologne, Germany, discussed a novel tandem cluster of differentiation (CD) 19 and CD20 chimeric antigen receptor (CAR)-T therapy for the treatment of patients with relapsed or refractory B cell non-Hodgkin lymphoma. Borchmann presented the 2-year follow up data from DALY 1 trial, which showed that beyond a favourable safety profile, zamtocabtagene autoleucel (MB-CART2019.1) led to durable complete remissions.
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Zamtocabtagene autoleuel (MB-CART2019.1):一种靶向CD19和CD20的CAR-T细胞产品,作为复发/难治性B细胞非霍奇金淋巴瘤患者的潜在治疗选择
在欧洲血液学协会(EHA) 2022年大会上,来自德国科隆大学的Peter Borchmann讨论了一种用于治疗复发或难治性B细胞非霍奇金淋巴瘤患者的新型串联分化(CD) 19和CD20嵌合抗原受体(CAR)-T疗法。Borchmann介绍了DALY 1试验的2年随访数据,该数据显示zamtocabtagene autoeucel (MB-CART2019.1)除了具有良好的安全性外,还能带来持久的完全缓解。
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