Prevention of coronary heart disease in black adults.

Cardiovascular clinics Pub Date : 1991-01-01
T A Pearson, G M Jenkins, J Thomas
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Abstract

Development of strategies to prevent CHD in blacks is impeded by the virtual absence of clinical trials demonstrating the feasibility and effectiveness of interventions in blacks. The wholesale generalization that interventions effective (or ineffective) in whites are similarly effective in blacks may risk the employment of worthless or even dangerous interventions in blacks. Using available epidemiologic data, a number of risk factors may be more important in blacks than whites by virtue of higher prevalence, increased relative risk, or both. These may include hypertension, lipoprotein (a), smoking, diabetes, and obesity. Thus, health agencies might emphasize these risk factors when developing preventive programs targeted at black populations. Prevention programs may best seek to prevent the onset of risk factors found highly prevalent in black communities, rather than the costly and side-effect-prone interventions to treat risk factors once established. Thus, there is a role for community-based as well as a high-risk approaches. The community-based approaches should seek to work with organizations such as churches, which traditionally play strong roles in the black community. Physicians treating black patients should be aware of the potentially different roles played by risk factors, and treat aggressively those individuals identified to be at high risk. Risk factor management should be emphasized, rather than reduced, in patients with already established CHD. CHD has been clearly shown to be preventable; both blacks and whites should benefit from specific interventions aimed toward this worthy goal.

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预防黑人成人冠心病。
由于几乎没有临床试验证明干预措施对黑人的可行性和有效性,因此阻碍了预防黑人冠心病策略的制定。如果一概而论地认为对白人有效(或无效)的干预措施对黑人也同样有效,就有可能在黑人中采用毫无价值甚至危险的干预措施。根据现有的流行病学数据,一些风险因素在黑人中可能比在白人中更重要,因为它们的流行率更高,相对风险增加,或两者兼而有之。这些因素可能包括高血压、脂蛋白(a)、吸烟、糖尿病和肥胖。因此,卫生机构在制定针对黑人的预防计划时,可以强调这些风险因素。预防计划的最佳目标可能是预防在黑人社区非常普遍的风险因素的发生,而不是在风险因素发生后采取昂贵且易产生副作用的干预措施进行治疗。因此,以社区为基础的方法和高风险方法都可以发挥作用。以社区为基础的方法应寻求与教会等组织合作,这些组织传统上在黑人社区发挥着重要作用。治疗黑人患者的医生应认识到风险因素可能发挥的不同作用,并积极治疗那些被确定为高风险的人。对于已经确诊的冠心病患者,应强调而不是减少风险因素管理。冠心病已被明确证明是可以预防的;黑人和白人都应从旨在实现这一目标的具体干预措施中获益。
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