Clinico-Biochemical findings associated with stage III and stage IV of Chronic Kidney Disease in dogs

Jayananthan Vinodhini, A. Abiramy Prabavathy, S. Uma, S. Barathiraja, K. Rajkumar, J. Thanislass, P. Vijayalakshmi
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Abstract

The present study on Chronic Kidney Disease (CKD) in dogs was aimed to record the incidence, risk factors, and clinical findings. Dogs irrespective of age, breed, sex with history, and clinical manifestations suggestive of CKD were selected and subjected to physical examination, urinalysis, hematology, and serum biochemistry. Based on these parameters twenty-nine dogs were identified as suffering from CKD and were classified into stage I, stage II, stage III, and stage IV as per the International Renal Interest Society (IRIS) staging system for CKD. Serum biochemistry revealed a significant increase in levels of serum creatinine, BUN, and cholesterol when compared to healthy controls. In conclusion, the prevalence of CKD in dogs was 2.5% and the article discussed the clinical and hemato-biochemical changes in CKD.
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犬慢性肾脏疾病III期和IV期的临床生化结果
本研究旨在记录犬慢性肾脏疾病(CKD)的发病率、危险因素和临床表现。选择犬只,不论年龄、品种、性别、有无CKD病史和临床表现,进行体格检查、尿液分析、血液学和血清生化。根据这些参数,29只狗被确定患有CKD,并根据国际肾脏利益协会(IRIS) CKD分期系统分为I期、II期、III期和IV期。血清生化显示,与健康对照组相比,血清肌酐、BUN和胆固醇水平显著升高。总之,狗的CKD患病率为2.5%,本文讨论了CKD的临床和血液生化变化。
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