DADNP: Dual Antibacterial Drug-Nanoparticle Systems Machine learning Approach

K. Diéguez-Santana
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Abstract

Abstract. The rise of new infectious diseases, combined with an increase in antibiotic resistance among bacterial pathogens, poses a significant health danger to humans. This ever-increasing threat of bacterial resistance necessitates the development of novel techniques to overcome this barrier. One of the successful strategies for combating antibiotic resistance has been the conjugation of nanoparticles (NPs) with antimicrobial moieties such as antibiotics, peptides, or other biomolecules. However, Dual Antibacterial Drug-Nanoparticle (DADNP) discovery is a slow
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双抗菌药物-纳米颗粒系统机器学习方法
摘要新的传染病的增加,加上细菌病原体中抗生素耐药性的增加,对人类的健康构成重大威胁。这种不断增加的细菌耐药性威胁需要开发新的技术来克服这一障碍。抗抗生素耐药性的成功策略之一是将纳米颗粒(NPs)与抗生素、多肽或其他生物分子等抗菌分子偶联。然而,双抗菌纳米药物(DADNP)的发现是一个缓慢的过程
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