Risk Factors for Acquired Muscle Weakness Among Critically all Patients

Ahmed El-Raghi Mostafa
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Abstract

: Background: One of the most common complications of Intensive Care Unit (ICU) is neuromuscular dysfunction due to critical illness, which may cause disuse atrophy. Large number of critically ill patients has severe muscle weakness, which has been named ICU-acquired weakness (ICU-AW). Purpose: The purpose of the study is to assess risk factors for acquired muscle weakness among Critical Ill Patients. Research Design: A descriptive exploratory design was utilized to achieve the purpose of this study. Setting: the study was conducted in the Intensive Care Units (ICUs) in Cairo University Hospital (general, chest and internal medicine ICU). Sampling: A Purposive sample of seventy-five patients admitted to the previous mentioned setting. Instruments: Three instruments were used for data collection. Instrument one: Characteristics of patients. Instrument two: muscle strength scale. Instrument three: - Factors contributing in Intensive Care Unit Acquired Muscle Weakness (ICU-AW) tool. Results : showed that more than half of studied patients had ICU-AW, most studied patients who had muscle weakness were older, abnormal WBCs level than the Non-ICU-AW patients. Administration of corticosteroid was higher in the ICU-AW patients than the Non-ICU-AW patients. There was no statistically significant relation between incidence of ICU-AW and gender, administration of parenteral nutrition and application of positioning, walking exercises. Conclusion: More than half of studied patients developed ICU-AW. The contributing factors of ICU-AW are patient age, abnormal WBCs level, not applying range of motion and chair sitting exercise to ICU patients, administration of corticosteroid. Recommendations: Further research is recommended to study extensively the effect of nutritional status on the incidence of ICU-AW. Also, the incidence of ICU-AW in sedated and unconscious patients’ needs to be assessed.
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危重患者获得性肌无力的危险因素
背景:重症监护病房(ICU)最常见的并发症之一是危重症所致的神经肌肉功能障碍,可能导致废用性萎缩。大量危重患者存在严重的肌无力,被称为icu获得性肌无力(ICU-AW)。目的:本研究的目的是评估危重病人获得性肌肉无力的危险因素。研究设计:采用描述性探索性设计达到本研究的目的。环境:研究在开罗大学医院的重症监护病房(普通科、胸科和内科ICU)进行。抽样:一个有目的的样本的75名患者入院前提到的设置。仪器:使用3台仪器进行数据收集。工具一:患者特征。仪器二:肌肉力量量表。工具三:影响重症监护病房获得性肌肉无力(ICU-AW)工具的因素。结果:超过一半的研究患者发生了ICU-AW,大多数研究的肌肉无力患者年龄较大,白细胞水平比非ICU-AW患者异常。ICU-AW患者的皮质类固醇用量高于非ICU-AW患者。ICU-AW的发生率与性别、肠外营养管理、体位、步行运动的应用无统计学意义。结论:半数以上的患者发生了ICU-AW。ICU- aw的影响因素有患者年龄、白细胞水平异常、ICU患者未进行活动范围和坐椅运动、使用皮质类固醇等。建议:建议进一步研究营养状况对ICU-AW发生率的影响。此外,需要评估镇静和无意识患者的ICU-AW发生率。
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