Usefulness of Measuring Serum LH Concentration on Day 1 Before Ovarian Stimulation in Non- Obese Polycystic Cases

Abstract

Background: Polycystic ovarian syndrome is associated with high LH related to infertility.Objectives: We aim at detecting the effect of day 1 LH on the outcome of controlled ovarian stimulationin slim PCOScases to determine a cut- off value for LH.Study design: We retrospectively analysed the out- come of stimulated cycles in PCOS cases with a body mass index 18-29 kg/m2 visiting the reproductive medicine clinic in El Shatby university hospital, Egypt. They were divided into two groups: Group A( LH less than or equal to 6IU/dl ) and Group B ( LH more than 6).Recombinent FEH was started day 2 and ovarian responce was monitored by folllicular scanning and serum estradiol (E2). HCG trigger was considered when the leading follicle is at least 18 mm, luteal phase was supported by vaginal micronised progesterone. Prenancy test in blood was done 16 days later.Results: significant difference was found in gonadotrophin dose and in pregnancy rate.Conclusion: Day 1 LH had a negative predictive value better than a positive predictive value for occurrence of pregnancy.