Gastric cancer patient characteristics in a city in the Central Anatolian Region of Turkey: A single-center descriptive study

Mustafa Büyükkör, Fatih Tay, Ayşegül Özakyol Harmancı
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Abstract

Aims: This study aimed to determine the characteristics of patients with gastric cancer living in Eskişehir, a city located in the central Anatolian region of Turkey, together with factors affecting the recurrence and survival time. Methods: This descriptive cross-sectional study was conducted using patients records who were admitted to Eskişehir Osmangazi University Health Practice and Research Hospital, Department of Internal Medicine between December 1998 and January 2011 with a diagnosis of gastric cancer. Missing data was obtained by calling the patients or their relatives by phone. Results: We evaluated 210 gastric cancer patients in this study.Male sex was approximately 2.5 times dominant, and most of the patients were diagnosed between the ages of 60-69. Approximately 1/5th of the patients applied to the health center 6 months after the onset of symptoms. Age, chemotherapy, and radiotherapy were significantly related to recurrence (p=0.028, p=0.009, and p=0.005, respectively). Stage, area of involvement, positive surgical margin, chemotherapy, radiotherapy, and the number of lymph nodes removed were significantly related to survival time (p<0.001 for all variables). Conclusion: In the studied population, gastric cancer diagnosis is delayed in a significant proportion of symptomatic patients. To decrease missed diagnoses, health professionals, especially those working in primary health care, should be made more sensitive towards the red flags of gastric cancer. Chemotherapy and radiotherapy are effective treatment options in preventing recurrences and improving survival.
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土耳其安纳托利亚中部地区某城市胃癌患者特征:单中心描述性研究
目的:本研究旨在确定居住在土耳其中部安纳托利亚地区eski ehir市的胃癌患者的特征,以及影响复发和生存时间的因素。方法:本描述性横断面研究采用1998年12月至2011年1月在eski Osmangazi大学卫生实践与研究医院内科就诊的诊断为胃癌的患者记录。缺失的数据是通过打电话给患者或其亲属获得的。结果:我们对210例胃癌患者进行了评估。男性占主导地位约2.5倍,大多数患者诊断年龄在60-69岁之间。大约1/5的患者在出现症状6个月后到卫生中心就诊。年龄、化疗、放疗与复发有显著相关性(p=0.028、p=0.009、p=0.005)。分期、受累面积、阳性手术切缘、化疗、放疗和淋巴结切除数与生存时间显著相关(所有变量p<0.001)。结论:在所研究的人群中,有症状的患者中有相当比例的胃癌诊断延迟。为了减少漏诊,卫生专业人员,特别是那些在初级卫生保健工作的人,应该对胃癌的危险信号更加敏感。化疗和放疗是预防复发和提高生存率的有效治疗选择。
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