Transdermal drug delivery: efficacy and potential applications of the penetration enhancer Azone.

Drug design and delivery Pub Date : 1990-06-01
J W Wiechers, R A de Zeeuw
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Abstract

In this review, the properties, pharmaceutical profile, and metabolism of Azone are described, and the mechanism of its action in facilitating transdermal drug delivery is discussed. It is concluded that the compound is safe for human use, and of value in enhancing the cutaneous absorption of many types of drugs.

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经皮给药:渗透增强剂氮酮的疗效和潜在应用。
本文综述了氮酮的性质、药理特征和代谢特性,并对其促进经皮给药的作用机制进行了讨论。结果表明,该化合物对人体是安全的,在促进多种药物的皮肤吸收方面具有一定的价值。
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