[Locally invasive oncocytoma of the nasal cavity].

H Martin, J Janda, H Behrbohm
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Abstract

Reported is a nasal oncocytoma with locally invasive properties in a 86 year old man. The tumor was histologically found to consist of cells rich in cytoplasm, with striking eosinophilia, granularity, and predominance of glandular architecture. Electron microscopy revealed typical oncocytes with abundant mitochondria in the cytoplasm, with many of them compressing the nuclei of tumor cells. The tumor reported was distinguished from unambiguously benign oncocytomas by its mitotic activity and locally invasive character. These properties should be noted in histologic diagnosis. Locally delimited but radical tumor removal is the adequate therapy.

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[鼻腔局部浸润性嗜瘤]。
报告一例86岁男性鼻嗜酸细胞瘤伴局部侵袭。组织学上发现肿瘤由富含细胞质的细胞组成,具有明显的嗜酸性细胞,颗粒状,腺结构为主。电镜显示典型的肿瘤细胞,细胞质中有丰富的线粒体,其中许多线粒体压迫肿瘤细胞核。根据其有丝分裂活性和局部侵袭性特征,将该肿瘤与明确的良性肿瘤细胞瘤区分开来。在组织学诊断时应注意这些特征。局部划界但根治性肿瘤切除是适当的治疗方法。
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