[Early neuropsychological changes in patients with nonalcoholic liver cirrhosis].

Abstract

The presence of latent encephalopathy was assessed by means of various psychodiagnostic tests in 24 non-alcoholic cirrhotics. Twenty-four subjects hospitalized for chronic extrahepatic conditions served as the control group. The following tests were utilized: 1) semistructured individual clinical interviews; 2) Rorschach test; 3) Minnesota Multiphasic Personality Inventory; 4) Reitan's test; 5) spatial capability test (hand test); 6) reaction times to sound and light stimulation. Mood and behavioural modifications were frequently found in cirrhotics, probably as a consequence of the reaction to a chronic disease. Such abnormalities could, however, be differentiated from the early impairment of superior psychomotor functions which were present in nearly 50% of cirrhotics as latent encephalopathy. Results indicate that the use of the Reitan's test, can allow for a better management of cirrhotics even at non advanced stages of the disease and that more sophisticated tests failed to add further clues to diagnosis of latent encephalopathy.