[Arterial hypertension following kidney transplantation in patients on conventional immunosuppressive therapy and in those treated with cyclosporin A].

Abstract

The frequency and the causes of arterial hypertension following renal transplantation were studied in 109 patients (110 renal transplantations). 75 patients with efficient renal function were followed up for one year. 46 + 2 of these patients received Azathioprin and 27 of them had arterial hypertension. Cycloeporin A received 29 + 2 patients and 18 of them had arterial hypertension. In the patients treated with Azathioprin a significantly greater frequency and higher values of the arterial pressure were found than in the patients treated with Cycloprorin A. A weak reverse relation was established between the arterial pressure and the serum cyclosporin A level. The arterial pressure was highest during the first month, slightly decreased at the third month and then rose again, later. Basic causes of arterial hypertension were the rejection reactions, the patients' own kidneys which were left in their place, arterial stenosis of the transplant.