The prevalence of carbohydrate metabolism disorders in patients after coronavirus infection

T. Markova, Anastasia A. Anchutina, Valeria Yu. Garib, T. O. Yalochkina
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Abstract

Introduction. A single-center observational cross-sectional comparative study was conducted among a random population sample of the adult population of the city of Moscow who applied to the pavilion "Healthy Moscow". The study included 796 patients who had a coronavirus infection from one to six months ago. Of the 796 surveyed, 112 participants had disorders of carbohydrate metabolism (hereinafter – DCM) (14.1%): 9.8% (78 people) were newly diagnosed with type 2 diabetes (D2t) of the total sample, prediabetes – 4.2% (33 people), type 1 diabetes – 0.1% (1 person). Previously diagnosed D2t was observed in 0.5% (4 participants) of the total sample of patients. Viral pneumonia was significantly more common in patients with DCM, compared with the group without DCM (45.5% vs. 19.1%, p<0.001). In the group of lung injuries, DCM were observed with greater frequency, including D2t, the probability of which in the presence of lung damage increased by 3.7 times (95% CI: 2.04 – 6.67). Thus, the prevalence of newly detected DCM after COVID-19 was 14.1%, and the more severe the coronavirus infection, the more likely the DCM will develop in the future. The study was carried out as part of the project of the Department of Health of the city of Moscow "Scientific laboratory "Moscow polyclinic". For citation: Markova T.N., Anchutina A.A., Garib V.Yu., Yalochkina T.O., The prevalence of carbohydrate metabolism disorders in patients after coronavirus infection. City Healthсare. 2022;3(4):32-41 doi:10.47619/2713-2617.zm.2022.v.3i4;32-41
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冠状病毒感染后患者碳水化合物代谢紊乱的患病率
介绍。在莫斯科市申请“健康莫斯科”展馆的成年人口随机抽样中进行了一项单中心观察横断面比较研究。该研究包括796名在一到六个月前感染冠状病毒的患者。在调查的796名参与者中,112名参与者患有碳水化合物代谢紊乱(以下简称DCM)(14.1%): 9.8%(78人)新诊断为2型糖尿病(D2t),糖尿病前期- 4.2%(33人),1型糖尿病- 0.1%(1人)。先前诊断的D2t在患者总样本的0.5%(4名参与者)中被观察到。病毒性肺炎在DCM患者中比无DCM组更常见(45.5%比19.1%,p<0.001)。肺损伤组出现DCM的频率更高,其中D2t在肺损伤时出现D2t的概率增加了3.7倍(95% CI: 2.04 ~ 6.67)。因此,新发现的DCM患病率为14.1%,冠状病毒感染越严重,未来发生DCM的可能性越大。这项研究是作为莫斯科市卫生局“科学实验室”“莫斯科综合诊所”项目的一部分进行的。引证:Markova t.n., Anchutina a.a., Garib v.u yu。冠状病毒感染后患者碳水化合物代谢紊乱的流行病学研究。城市卫生с。3 (4): 2022; 32-41 doi: 10.47619 / 2713 - 2617. - zm.2022.v.3i4; 32-41
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