Comparison between oxytocin intravenous bolus, oxytocin intravenous bolus and infusion, rectal misoprostol and carbetocin infusion for the control of blood loss at elective cesarean section

Abstract

Background: Uterine atony is the greatest typical etiology of primary postpartum hemorrhage (PPH). The atonic PPH rates of developed nations are rising despite regular active control of the third stage of work. Primary PPH continues to be the greatest cause of maternal mortality in less developed nations. Aim and objectives: To assess the effectiveness of rectal misoprostol, oxytocin infusion, and oxytocin intravenous bolus and infusion in reducing blood loss during and after elective caesarean delivery. Patients and methods: This prospective research included 200 pregnant patients who were hospitalized to the labor ward at the Department of Obstetrics and Gynecology of Al-Hussein University Hospital. Result: There was a significant difference among included groups regarding additional uterotonic use intraoperatively, as it was used in 17, 12, 13, and 5 in groups 1, 2, 3, and 4, respectively. Conclusion: Compared with the oxytocin and misoprostol groups, carbetocin is only effective in reducing postpartum bleeding and is related with a reduced requirement for further uterotonic medicines or surgical hemostatic treatments.