Cognitive Impairment and Dementia in Geriatric Population: Role of Clinical Laboratory

Abhik K Banerjee, G. Das, Rajarshi Sil
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Abstract

Mild cognitive impairment is an intermediate stage between the expected cognitive decline of normal ageing and the more serious decline of dementia. Dementia is typically diagnosed when acquired cognitive impairment has become severe enough to compromise social and/or occupational functioning. The elderly are at much greater risk for cognitive impairment. Unfortunately, most cases of cognitive impairment without apparent dementia go undetected and thereby untreated in primary care. Clinical diagnosis supported by appropriate use of diagnostic tests and biomarker is essential to improve the quality of life in these patients. In this article, we discussed the role of clinical laboratories in the diagnosis of cognitive impairment and dementia in the geriatric population.
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老年人群的认知障碍和痴呆:临床实验室的作用
轻度认知障碍是介于正常衰老预期的认知能力下降和更严重的痴呆下降之间的中间阶段。当获得性认知障碍严重到足以损害社会和/或职业功能时,通常会诊断出痴呆症。老年人患认知障碍的风险要大得多。不幸的是,大多数没有明显痴呆的认知障碍病例未被发现,因此在初级保健中得不到治疗。在适当使用诊断测试和生物标志物的支持下进行临床诊断对于改善这些患者的生活质量至关重要。在这篇文章中,我们讨论了临床实验室在老年人群认知障碍和痴呆诊断中的作用。
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