Genetic and molecular mechanisms of neurogenesis in Drosophila melanogaster.

Journal de physiologie Pub Date : 1990-01-01
J A Campos-Ortega, E Knust
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Abstract

Cells of the neurogenic ectoderm of insects have to decide between a neural and an epidermal fate. In Drosophila, this decision id mediated by cellular interactions. The products of two different groups of genes, i.e., the neurogenic genes and the genes of the achaete-scute complex and daughterless, seem to provide the molecular basis for the elements of a signal chain that permits the commitment of the cells to a given fate.

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黑腹果蝇神经发生的遗传和分子机制。
昆虫的神经源性外胚层细胞必须在神经细胞和表皮细胞之间做出选择。在果蝇中,这种决定是由细胞相互作用介导的。两组不同基因的产物,即神经源性基因和无毛鳞片复合体和无子代的基因,似乎为信号链的元素提供了分子基础,这些元素允许细胞承担特定的命运。
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Control of the maturation and the survival of central noradrenergic neurons in culture. Expression of T-type calcium current precedes neurite extension in neuroblastoma cells. Synaptic formations and modulations of synaptic transmissions between identified cerebellar neurons in culture. Regulation of neurotransmitter synthesis: from neuron to gene. In vitro and in vivo regulation of the expression of the tyrosine hydroxylase gene.
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