M. Weilguni, W. Smetana, M. Edetsberger, G. Kohler
{"title":"Bladder cancer cell imaging system","authors":"M. Weilguni, W. Smetana, M. Edetsberger, G. Kohler","doi":"10.1109/ISSE.2009.5206970","DOIUrl":null,"url":null,"abstract":"A system for observing bladder cancer cells in form of a miniaturized fluorescence microscope has been developed. Attention has turned to integrate this system in an existing LTCC (Low Temperature Cofired Ceramics) module. Software with a region detecting algorithm has been written to automatically detect the captured images. The cancer specimen was marked with hypericin, which is selective on bladder cancer cells. After coloring the specimen was excited with green light of a high power LED. The red emitting hypericin marked cells were captured by a CMOS chip and evaluated with the software to confirm or negate a suspicion of cancer.","PeriodicalId":337429,"journal":{"name":"2009 32nd International Spring Seminar on Electronics Technology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 32nd International Spring Seminar on Electronics Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISSE.2009.5206970","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
A system for observing bladder cancer cells in form of a miniaturized fluorescence microscope has been developed. Attention has turned to integrate this system in an existing LTCC (Low Temperature Cofired Ceramics) module. Software with a region detecting algorithm has been written to automatically detect the captured images. The cancer specimen was marked with hypericin, which is selective on bladder cancer cells. After coloring the specimen was excited with green light of a high power LED. The red emitting hypericin marked cells were captured by a CMOS chip and evaluated with the software to confirm or negate a suspicion of cancer.
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