[Dependence of serum hormones (T, FSH, LH) on morphometric testicular findings after chemo- and radiotherapy in patients with malignant testicular tumors].

V Barth, M Schönfelder
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Abstract

Correlations which exist between morphometric parameters of remaining testicular tissue, on the one hand, and serum hormones on the other (testosterone = T, follicle-stimulating hormone = FSH, luteinising hormone = LH), depending on therapeutic action taken on patients for malignant testicular tumours, seem to suggest that decline in epithelial thickness together with increase in wall thickness leads to rise in FSH. No unambiguous relations, on the other hand, were found to exist between testosterone or luteotrophic hormone and morphometric findings. Hence, FSH seems to characterise the severity of damage to germ epithelium and thus the degree of impairment to spermatogenesis. FSH may be accepted as a criterion for fertility disorders in sexually active men.

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[睾丸恶性肿瘤患者化疗和放疗后血清激素(T、FSH、LH)对睾丸形态测量的依赖性]。
剩余睾丸组织形态测量参数与血清激素(睾酮= T,促卵泡激素= FSH,促黄体生成素= LH)之间存在相关性,这取决于对恶性睾丸肿瘤患者所采取的治疗措施,似乎表明上皮厚度的下降与壁厚的增加导致FSH升高。另一方面,睾酮或黄体促生激素与形态测量结果之间没有明确的关系。因此,卵泡刺激素似乎表征了生殖上皮损伤的严重程度,从而表征了精子发生损伤的程度。FSH可作为性活跃男性生育障碍的标准。
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