Review of synthesis of mono, bis and tris-1,3,4- oxadiazole and N-substituted-2,5-disubstituted-1,3,4- oxadiazole

Abstract

In this minireview, the method of syntheses of mono, bis and tris-1,3,4-oxadiazole and N-substituted-2,5-disubstituted-1,3,4- oxadiazole is reviewed. To the best of my knowledge, reviews on the mono 1,3,4-oxadiazoles are extensive while now reviews are reported to cover the syntheses of the bis and tris counterparts. The bis and tris 1,3,4-oxadiazoles and N-substituted-2,5-disubstituted-1,3,4-oxadiazole and their precursors and derivatives are promising candidates for many different applications in industry notably the medicinal and pharmaceutical industries.