{"title":"Tuberculostatic activity of henna (Lawsonia inermis Linn.)","authors":"V.K. Sharma","doi":"10.1016/0041-3879(90)90044-9","DOIUrl":null,"url":null,"abstract":"<div><p>The tuberculostatic activity of the herb henna (<em>Lawsonia inermis</em> Linn.) was tested <em>in vitro</em> and <em>in vivo</em>. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of <em>Mycobacterium tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv was inhibited by 6 μg/ml of the herb. <em>In vivo</em> studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with <em>M. tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv.</p></div>","PeriodicalId":23472,"journal":{"name":"Tubercle","volume":"71 4","pages":"Pages 293-295"},"PeriodicalIF":0.0000,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0041-3879(90)90044-9","citationCount":"86","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tubercle","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0041387990900449","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 86
Abstract
The tuberculostatic activity of the herb henna (Lawsonia inermis Linn.) was tested in vitro and in vivo. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of Mycobacterium tuberculosis H37Rv was inhibited by 6 μg/ml of the herb. In vivo studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with M. tuberculosis H37Rv.
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