Effects of electrotherapy in neuropathic pain management in patients with diabetic peripheral neuropathy: A narrative review

M. Karypidou, D. Lytras, Anastasios Kottaras, Paris Iakovidis, Andreas Fotios Tsimerakis, Georgios, Leptourgos
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Abstract

Diabetes is one of the most prevalent diseases worldwide and Diabetic Peripheral Neuropathy (DPN) is the most common neuropathic syndrome affecting approximately 50% of patients with type 2 diabetes. One of its main clinical manifestations is neuropathic pain, which significantly complicates the daily life of patients and leads to a low quality of life related to health. The aim of this review is to describe research data on the means of electrotherapy used and their effects in the treatment of pain in patients with DPN. The PubMed, PEDro, Scopus and Google Scholar databases were searched in English with the following keywords: Diabetic Painful Neuropathy, Low-level Laser Therapy, Transcutaneous Electrical Nerve Stimulation, and Electromagnetic Fields. The review included 10 clinical studies published in the period of 2004-2019. Discussion-Conclusions: Low-power lasers, pulsed electromagnetic fields and Transcutaneous Electrical Nerve Stimulation (TENS) are treatment options for treating neuropathic pain in patients with DPN and are considered safe, effective, with minimal side effects compared to medication. However, diabetic neuropathic pain remains a challenge for health scientists. Although there is scientific evidence for the contribution of electrotherapy to its treatment, more focused research is needed.
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电疗在糖尿病周围神经病变患者神经性疼痛治疗中的作用:一项叙述性综述
糖尿病是世界上最常见的疾病之一,糖尿病周围神经病变(DPN)是最常见的神经病变综合征,影响约50%的2型糖尿病患者。其主要临床表现之一是神经性疼痛,使患者的日常生活变得非常复杂,导致与健康相关的生活质量降低。本综述的目的是描述电疗方法的研究数据及其在治疗DPN患者疼痛方面的效果。用英文检索PubMed、PEDro、Scopus和Google Scholar数据库,检索关键词为:糖尿病性疼痛性神经病变、低水平激光治疗、经皮神经电刺激和电磁场。该综述包括2004-2019年期间发表的10项临床研究。讨论-结论:低功率激光、脉冲电磁场和经皮神经电刺激(TENS)是治疗DPN患者神经性疼痛的治疗选择,与药物相比,这些治疗被认为是安全、有效的,副作用最小。然而,糖尿病神经性疼痛对健康科学家来说仍然是一个挑战。虽然有科学证据表明电疗对其治疗的贡献,但需要更有针对性的研究。
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