Post-necrotising enterocolitis pseudo-obstruction treated with Cisapride.

J M Vanderwinden, M Dassonville, E Van der Veken, S Cadranel, M H De Laet
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引用次数: 1

Abstract

We report on one patient in whom segmental colic intestinal pseudo-obstruction (IPO) following the surgical treatment of a grade III necrotising enterocolitis (NEC) was responsible for a severe failure to thrive. Further intestinal resection in an already short gut was avoided by using Cisapride, a new intestinal prokinetic agent (1 mg/kg/d in 4 doses, orally), which dramatically improved the symptoms and allowed weight gain and intestinal adaptation. After 6 months, Cisapride was withdrawn. IPO did not recur after 2 years of follow-up, although proximal distention persisted.

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西沙比利治疗坏死性小肠结肠炎假性梗阻。
我们报告了一位III级坏死性小肠结肠炎(NEC)手术治疗后的节段性结肠假性梗阻(IPO)导致严重的生长失败的患者。西沙匹利是一种新的肠道促动力剂(1 mg/kg/d,分4次口服),可避免在已经很短的肠道中进一步切除肠道,可显著改善症状,并允许体重增加和肠道适应。6个月后停用西沙必利。尽管近端腹胀持续存在,但2年随访后IPO未复发。
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