The effect of Laparoscopic Ovarian Drilling on Anti-Müllerian Hormone, LH/FSH ratio & Inhibin B

Abstract

Aim of The Work: Comparing AMH to other parameters of ovarian reserve (OR) in evaluating the effect of laparoscopic ovarian drilling (LOD) on OR in treatment of PCO.Results: The mean AMH level before the operation was 6.9±1.4 ng/ml & 8.2±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean AMH level after 3 months of the operation was 5.1±1.1 ng/ml & 6.3±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. The mean LH/FSH ratio before the operation was 2.04±0.5 & 3.02±0.6 for the patients who got pregnant and those who did not get pregnant respectively. While the mean LH/FSH ratio after 3 months of the operation was 1.15±0.2 & 1.93±0.6 for the patients who got pregnant and those who did not get pregnant respectively. The mean inhibin B level before the operation was 52.5±2.2 pg/ml & 52.6±3.9 pg/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean inhibin B level after 3 months of the operation was 48.3±2.1 pg/ml & 49.1±3.6 pg/ml for the patients who got pregnant and those who did not get pregnant respectively.Conclusion: Pregnancy rates were significantly related to the preoperative LH/FSH ratio & AMH levels when comparing the cases that got pregnant with the cases who did not conceive postoperatively in patients of polycystic ovary syndrome (PCOS), whereas preoperative Inhibin B level had no relation to pregnancy rates .