La eyaculación no tiene impacto en los niveles de antígeno prostático específico

M. Ramírez-Bonilla, C.I. Villeda-Sandoval, G. Romero-Vélez, A. Lisker-Cervantes, J.J. Cendejas-Gómez, B. González-Sánchez, D. Olvera-Posada, M. García-Sánchez, R.A. Castillejos-Molina, M. Sotomayor-de Zavaleta
{"title":"La eyaculación no tiene impacto en los niveles de antígeno prostático específico","authors":"M. Ramírez-Bonilla,&nbsp;C.I. Villeda-Sandoval,&nbsp;G. Romero-Vélez,&nbsp;A. Lisker-Cervantes,&nbsp;J.J. Cendejas-Gómez,&nbsp;B. González-Sánchez,&nbsp;D. Olvera-Posada,&nbsp;M. García-Sánchez,&nbsp;R.A. Castillejos-Molina,&nbsp;M. Sotomayor-de Zavaleta","doi":"10.1016/j.uromx.2015.07.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Prostate-specific antigen (PSA) is a tumor marker used in the diagnosis of prostate cancer; it is organ-specific but it is not disease-specific. The effect of ejaculation on PSA concentration is controversial.</p></div><div><h3>Aim</h3><p>To evaluate the impact of PSA values after ejaculation on biopsy indication in a screened population.</p></div><div><h3>Methods</h3><p>Baseline PSA was measured in 100 patients that had abstained from sexual activity for at least 7<!--> <!-->days. A second measurement was carried out 48<!--> <!-->h after ejaculation. The numerical differences were compared using the Student's t test. The McNemar's test was used to analyze pre and post-ejaculation values and clinical significance was defined as a PSA value above a pre-established limit for biopsy indication.</p></div><div><h3>Results</h3><p>Mean age of the patients was 52.7<!--> <!-->±<!--> <!-->8.6<!--> <!-->years. The mean baseline PSA was 1.39<!--> <!-->±<!--> <!-->1.43<!--> <!-->ng/mL and after ejaculation was 1.48<!--> <!-->±<!--> <!-->1.51<!--> <!-->ng/mL (<em>P</em> <!-->=<!--> <!-->.54). Two patients had PSA values that increased sufficiently for biopsy indication, using a parameter of 4<!--> <!-->ng/mL after ejaculation. The McNemar's test showed no statistically significant differences (<em>P</em> <!-->=<!--> <!-->.500).</p></div><div><h3>Conclusions</h3><p>There was no statistically significant difference in PSA after ejaculation and this change had no clinical relevance.</p></div>","PeriodicalId":34909,"journal":{"name":"Revista mexicana de urologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uromx.2015.07.004","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista mexicana de urologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2007408515001032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background

Prostate-specific antigen (PSA) is a tumor marker used in the diagnosis of prostate cancer; it is organ-specific but it is not disease-specific. The effect of ejaculation on PSA concentration is controversial.

Aim

To evaluate the impact of PSA values after ejaculation on biopsy indication in a screened population.

Methods

Baseline PSA was measured in 100 patients that had abstained from sexual activity for at least 7 days. A second measurement was carried out 48 h after ejaculation. The numerical differences were compared using the Student's t test. The McNemar's test was used to analyze pre and post-ejaculation values and clinical significance was defined as a PSA value above a pre-established limit for biopsy indication.

Results

Mean age of the patients was 52.7 ± 8.6 years. The mean baseline PSA was 1.39 ± 1.43 ng/mL and after ejaculation was 1.48 ± 1.51 ng/mL (P = .54). Two patients had PSA values that increased sufficiently for biopsy indication, using a parameter of 4 ng/mL after ejaculation. The McNemar's test showed no statistically significant differences (P = .500).

Conclusions

There was no statistically significant difference in PSA after ejaculation and this change had no clinical relevance.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
射精对前列腺特异性抗原水平没有影响
前列腺特异性抗原(PSA)是一种用于前列腺癌诊断的肿瘤标志物;它是器官特异性的,但不是疾病特异性的。射精对PSA浓度的影响存在争议。目的评价筛查人群射精后PSA值对活检指征的影响。方法对100例禁欲至少7天的患者进行基线PSA测定。第二次测量在射精后48小时进行。采用学生t检验比较数值差异。McNemar试验用于分析射精前和射精后的PSA值,其临床意义定义为PSA值高于预先确定的活检指征限度。结果患者平均年龄52.7±8.6岁。平均基线PSA为1.39±1.43 ng/mL,射精后PSA为1.48±1.51 ng/mL (P = 0.54)。两名患者的PSA值在射精后达到4ng /mL,足以用于活检指示。McNemar检验显示无统计学显著差异(P = .500)。结论射精后PSA水平差异无统计学意义,且无临床意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Revista mexicana de urologia
Revista mexicana de urologia Medicine-Urology
CiteScore
0.20
自引率
0.00%
发文量
49
期刊介绍: Revista Mexicana de Urología (RMU) [Mexican Journal of Urology] (ISSN: 0185-4542 / ISSN electronic: 2007-4085) is bimonthly publication that disseminates research by academicians and professionals of the international medical community interested in urological subjects, in the format of original articles, clinical cases, review articles brief communications and letters to the editor. Owing to its nature, it is publication with international scope that disseminates contributions in Spanish and English that are rigorously reviewed by peers under the double blind modality. Neither journalistic documents nor those that lack rigorous medical or scientific support are suitable for publication.
期刊最新文献
Fe de errores de «Resultados obtenidos con nefrolitotomía percutánea y su correlación con las escalas de Guy y S.T.O.N.E. en un hospital de la Ciudad de México» [Rev Mex Urol. 2016;76:331] Blindness due to a systemic fungal infection in a patient with a ureteral catheter Permixon® en el tratamiento de los síntomas del tracto urinario inferior por hiperplasia benigna de próstata: Nuevas aportaciones Resultados de la nefrectomía laparoscópica en pacientes obesos y no obesos Alfa-1 bloqueantes y resultados urodinámicos en varones con síntomas del tracto urinario inferior relacionados con obstrucción benigna de próstata: ¿fin de la controversia?
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1