[Variation in manifestations of bronchopulmonary aspergillosis].

P Rozánek, M Otcenásek, I Steiner, K Mencl
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Abstract

Five cases of bronchopulmonary aspergillosis are scrutinized which showed no unambiguous account for any of 6 forms of the disease as described previously. Clinical signs, roentgenograms and bronchoscopy findings testified about the interaction between the aspergillus and the host being in accord with either the aspergilloma or chronical necrotizing pulmonary aspergillosis. Authors preclude the invasive symptomatology represents a developmental and likely initial phase in aspergilloma's onset. Apart from the disease progression, markedly extinctive signs of aspergilloma's activity have in contrast been detected after a period of its duration. In this case, the important signs are associated rather with the occurrence of other microorganisms whose participation was proved in 3 from 5 patients. Authors suggest also the immune status of those affected and the process invasiveness should be taken in mind in providing etiotropic treatment with the impact on the spectrum of microorganisms detected.

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[支气管肺曲霉病表现的变化]。
对5例支气管肺曲霉病进行了仔细检查,结果表明,前面所述的6种形式的疾病没有明确的解释。临床体征、x线片和支气管镜检查结果证实,曲霉与宿主的相互作用符合曲霉瘤或慢性坏死性肺曲霉病。作者排除了侵袭性症状代表了曲菌瘤发病的一个发育和可能的初始阶段。除了疾病进展外,曲菌瘤活动的明显消失迹象在持续一段时间后被检测到。在这种情况下,重要的迹象与其他微生物的出现有关,其中5名患者中有3名被证明参与了其他微生物。作者还建议,在提供致病因治疗时,应考虑到受影响者的免疫状态和过程的侵袭性,以及对检测到的微生物谱的影响。
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