Retinal imaging with photoreceptor resolution

S. Nascimento, H. T. Correia, Sandra Franco, Jose Manuel Borges de Ameida
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Abstract

Retinal imaging capable of resolving individual photoreceptors cannot be obtained with conventional ophthalmoscopy but requires compensation of the individual optical aberrations that blur the optical image from the fundus. This optical compensation is normally accomplished by adaptive optics. We built a retinal imaging system based on adaptive optics can image individual cone photoreceptors. The system uses infrared radiation from a superluminescent diode (SLD) and a Hartman-Shack wavefront sensor to measure eye aberrations. An ophthalmoscope channel with a digital camera is integrated with the system to visualize the retina. A deformable mirror is used to partially compensate the aberrations of the light from the eye thereby improving the image quality and optical resolution. Images from the fundus were obtained from one healthy retina at about 0.5-1.0 deg eccentricity. The cone photoreceptor mosaic is visible and individual photoreceptors can be inspected.
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视网膜成像与光感受器分辨率
能够分辨单个光感受器的视网膜成像不能通过传统的眼科检查获得,但需要补偿从眼底模糊光学图像的单个光学像差。这种光学补偿通常由自适应光学来完成。我们建立了一个基于自适应光学的视网膜成像系统,可以对单个视锥光感受器进行成像。该系统使用来自超发光二极管(SLD)和哈特曼-沙克波前传感器的红外辐射来测量眼像差。带有数码相机的检眼镜通道与该系统集成,以可视化视网膜。可变形反射镜用于部分补偿来自眼睛的光的像差,从而提高图像质量和光学分辨率。眼底图像取自一个健康视网膜,偏心率约0.5-1.0度。视锥光感受器马赛克可见,单个光感受器可以检查。
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