Treatment with an LHRH analogue in patients with advanced pancreatic cancer. A preliminary report.

Acta chirurgica Scandinavica Pub Date : 1990-08-01
A Andrén-Sandberg
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Abstract

Ten patients with non-extirpable adenocarcinoma of the pancreas received monthly subcutaneous implantations of the LHRH analogue goserelin. Subjective improvement (diminished abdominal pain and/or weight gain) occurred within 3 months in seven patients and persisted until about 2 months before death. The treatment was well tolerated by the patients. This preliminary study seems to warrant further investigation of goserelin in the management of pancreatic cancer.

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LHRH类似物治疗晚期胰腺癌患者。初步报告。
10例不可清除性胰腺腺癌患者每月接受LHRH类似物戈舍林的皮下植入。7例患者主观改善(腹痛减轻和/或体重增加)在3个月内出现,并持续到死亡前约2个月。病人对这种治疗耐受良好。这一初步研究似乎值得进一步研究戈舍雷林在胰腺癌治疗中的作用。
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Idiopathic retroperitoneal fibrosis. Atrial septal defects. Prevention of adhesions by high molecular weight dextran in rats. Re-evaluation in nine experiments. Relevant factors in the prognosis of ductal pancreatic carcinoma. A comparison of polypropylene mesh, expanded polytetrafluoroethylene patch and polyglycolic acid mesh for the repair of experimental abdominal wall defects.
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