History of development of the concept and definition for “Probiotics” and “Prebiotics” and their perspective for future consensus

T. Sako
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Abstract

The terms “Probiotics” and “Prebiotics” which represent beneficial microbes and beneficial food substances for human health, respectively, have been used for several decades since they were firstly developed. The original ideas showing the importance of the gut microbiota for health were already argued more than a hundred years ago, and since then many efforts to demonstrate and practice the actual beneficial effects of certain microbes and substances have been implemented by a huge number of investigators. In this review article, I would like to summarize the history of argument of the concepts and definitions for “Probiotics” and “Prebiotics”, and see how we can find appropriate ways to reach future consensus.
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“益生菌”和“益生元”的概念和定义的发展历史及其对未来共识的展望
“益生菌”和“益生元”这两个术语分别代表对人类健康有益的微生物和有益的食物物质,自它们最初被发明以来,已经使用了几十年。证明肠道菌群对健康的重要性的最初想法早在一百多年前就已经有人提出了,从那时起,大量的研究人员开始努力证明和实践某些微生物和物质的实际有益作用。在这篇综述文章中,我想总结“益生菌”和“益生元”的概念和定义的争论历史,看看我们如何找到合适的方法来达成未来的共识。
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Anticipation of probiotics usage under “prudent use of antimicrobials for animal therapy” 乳酸菌とビフィズス菌のサイエンスの発展 次世代シーケンサーデータの解析手法 第 18 回 遺伝子発現データのクラスタリング Exploratory analysis on the genomic data of lactic acid bacteria in the public sequence database Aerobic fed-batch culture of lactic acid bacteria
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