Local Infiltration of Bupivacaine versus Placebo for Post-Operative Pain Relief Following Elective Lichtenstein Hernioplasty: A Randomized Controlled Trial

A. Rashid, M. Bhat, Sheikh Junaid, M. Mushtaque
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Abstract

Introduction: Postoperative pain relief is of paramount importance in any surgery. Objective: To compare the effect of local infiltration of bupivacaine versus placebo for post-operative pain relief following inguinal hernioplasty. Materials and Methods: Ours was a prospective randomized controlled trial conducted on 120 patients undergoing elective Lichtenstein hernioplasty. Patients were divided into two groups of 60 each. One group received local infiltration with 10 mL bupivacaine 0.25% below the external oblique aponeurosis and 15 mL bupivacaine 0.25% subcutaneously after completion of the surgical procedure. The other group received an equal amount of normal saline infiltrated in the similar manner. Visual Analogue Scale measured the pain. Results: The baseline parameters were similar in both the groups. Postoperative pain was significantly decreased in patients receiving bupivacaine (p < 0.05). Mean time to first request for rescue analgesic was increased from 245 + 19.42 minutes to 472 + 19.42 minutes (p < 0.05). The consumption of supplementary analgesics during the 24-hour study period reduced from a mean of 2.8 + 0.12 to 1.7 + 0.09 doses in bupivacaine group (p < 0.05). Conclusion: Local infiltration of bupivacaine is an effective modality for post-operative pain relief in inguinal hernioplasty.
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选择性利希滕斯坦疝成形术后局部浸润布比卡因与安慰剂的术后疼痛缓解:一项随机对照试验
术后疼痛的缓解在任何手术中都是至关重要的。目的:比较布比卡因局部浸润与安慰剂在腹股沟疝成形术后疼痛缓解中的作用。材料和方法:我们是一项前瞻性随机对照试验,对120例接受选择性利希滕斯坦疝成形术的患者进行了研究。患者被分为两组,每组60人。一组手术结束后,在腹外斜腱膜下局部浸润10 mL 0.25%布比卡因,皮下浸润15 mL 0.25%布比卡因。另一组以相同方式浸润等量生理盐水。视觉模拟量表测量疼痛。结果:两组的基线参数相似。布比卡因组术后疼痛明显减轻(p < 0.05)。平均到第一次请求镇痛药的时间由245 + 19.42 min增加到472 + 19.42 min (p < 0.05)。布比卡因组在24小时研究期间补充镇痛药的用量从平均2.8 + 0.12剂减少到1.7 + 0.09剂(p < 0.05)。结论:布比卡因局部浸润是缓解腹股沟疝成形术术后疼痛的有效方式。
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