Prevalence of hepatitis B virus (HBV) in Italian adolescents.

V Di Ciommo, F Ferrario, G Spina, F La Spesa, S Rubino
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Abstract

Prevalence of HBV markers (HbsAg, anti-Hbs, anti-HBc) was retrospectively estimated in 204 adolescents (12-20 years old) of the Bambino Gesù Hospital (174 patients of orthopaedic department and 30 student nurses). HBsAg carrier rate was 3.4% (all healthy, none HBeAg positive) and prevalence of HBV marker (at least one positive) was 13.2%. Male sex, residence in the south of Italy or Italian islands, being inpatients, past surgical procedures and past hepatitis showed higher prevalences, but never significantly; anti-HBc prevalence was significantly higher in patients with a previous surgical procedure with transfusions. Future vaccinations should take into account the substantial HBV infection rate occurred as early as in adolescence.

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意大利青少年乙型肝炎病毒(HBV)患病率
回顾性评估了Bambino Gesù医院204名(12-20岁)青少年(174名骨科患者和30名实习护士)的HBV标志物(HbsAg、anti-Hbs、anti-HBc)的流行情况。HBsAg携带者率为3.4%(全部健康,无HBeAg阳性),HBV标志物(至少一个阳性)患病率为13.2%。男性、居住在意大利南部或意大利岛屿、住院患者、既往外科手术和既往肝炎均显示较高的患病率,但从未显著升高;有过输血手术的患者抗hbc患病率明显更高。未来的疫苗接种应考虑到早在青春期就发生的大量HBV感染率。
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