PENGARUH PEMBENTUK FILM PVA PADA SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL BAWANG DAYAK (Eleutherina palmifolia (L.) Merr) TERHADAP AKTIVITAS ANTIBAKTERI Staphylococcus aureus PENYEBAB JERAWAT

Husnani Husnani, Fitri Sri Rizki
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引用次数: 3

Abstract

ABSTRACTDayak Onion (Eleutherine palmifolia) is one of the plants that can inhibit Staphylococcus aureus bacteria that causes acne. This study aims to determine the effect of polyvinyl alcohol on peel-off gel mask preparations from onion dayak ethanol extract on the antibacterial activity of Staphylococcus aureus that causes acne. Extraction using maceration method with 96% ethanol. The concentration of dayak onion extract was made at 5%, 7.5%, and 10% and the peel-off gel mask formula from dayak onion extract with variations in extract concentration were 5%, 7.5%, and 10% based on Polyvinyl Alcohol (PVA). Antibacterial activity is carried out using the disk disc method. In testing the inhibition of dayak onion extract at a concentration of 5% resulted in a clear zone of 15.5 mm, a concentration of 7.5% and 10% producing the same clear zone diameter of 17.1 mm. The peel-off gel mask in formulation I obtained a clear zone diameter of 8.7 mm, formulation II the diameter of the clear zone was 12.2 mm, and formula III the diameter of the clear zone was 15.3 mm. The results of this study indicate that on dayak onion extract has a greater inhibitory power compared to the dayak onion extract peel-off gel mask preparation. It can be concluded that the PVA in the preparation affects the amount of inhibitory power on the bacteria forming acne, namely Staphylococcus aureus.Keywords: Dayak onion extract, Staphylococcus aureus, disk discs, antibacterial inhibitory test, acne-causing bacteria, peel-off gel mask.
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PVA制片效果在剂型凝胶凝胶中提取洋葱DAYAK乙醇(Eleutherina palmifolia, L)。治疗痤疮的葡萄球菌菌活性
摘要大葱(Eleutherine palmifolia)是一种能抑制引起痤疮的金黄色葡萄球菌的植物。本研究旨在确定聚乙烯醇对洋葱大黄乙醇提取物剥脱凝胶面膜制剂对引起痤疮的金黄色葡萄球菌的抑菌作用。用96%乙醇浸渍法提取。以聚乙烯醇(PVA)为原料,分别在5%、7.5%、10%的浓度下制备大葱提取物,得到浓度分别为5%、7.5%、10%的大葱提取物去皮凝胶面膜配方。抗菌活性采用圆盘法进行。在试验中,当浓度为5%时,大葱提取物的抑制效果为15.5 mm,当浓度为7.5%和10%时,其抑制效果相同,为17.1 mm。配方1的剥脱式凝胶面膜的清区直径为8.7 mm,配方2的清区直径为12.2 mm,配方3的清区直径为15.3 mm。本研究结果表明,大葱提取物比大葱提取物剥脱凝胶面膜具有更大的抑制作用。由此可见,制剂中的PVA影响了对形成痤疮的细菌即金黄色葡萄球菌抑制力的大小。关键词:大葱提取物,金黄色葡萄球菌,盘片,抑菌抑制试验,致痘细菌,可剥凝胶面膜。
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