Epidemiology of hand foot and mouth disease in mainland of China,2008-2009

Wang Li
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引用次数: 3

Abstract

Objective To analyze the epidemiological characteristics of hand foot and mouth disease(HFMD) in the mainland of China during 2008-2009.Methods The analysis was conducted on the incidence data of HFMD during 2008-2009 collected from the national disease reporting information system.Results A total of 1 664 480 cases of HFMD,including 14 977 severe cases and 479 deaths,were reported during this period.As time goes on,the disease spread gradually from central area to eastern,southern and northern areas.The reported case numbers declined in 2009 in the areas with high case numbers in 2008.Most cases were children aged5 years,accounting for 93.86% of the total.Among these cases,those in children age3 years accounted for 79.69%.The risks to become severe case or of death were greater in age group of 1-2 than in other groups.Totally 30 953 cases were laboratory confirmed,of which EV71 infections,Cox A16 infections and other enteric virus infections accounted for 50.81%,28.27% and 20.93% respectively.Conclusion In recent 2 years,the incidence of HFMD and the incidences of severe cases and deaths caused by EV71 infection increased substantially in the mainland of China.,which resulted in serious disease burden and public health problem.In the areas where EV71 is predominant,it is necessary to take effective intervention measures in early phase and strengthen the medical treatment of severe cases to reduce the case fatality.Further study should be conducted on the technical problems still existed in the prevention and control of HFMD.
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2008-2009年中国大陆手足口病流行病学分析
目的分析2008-2009年中国大陆手足口病流行病学特征。方法对全国疾病报告信息系统2008-2009年手足口病发病数据进行分析。结果全年共报告手足口病1 664 480例,重症14 977例,死亡479例。随着时间的推移,该病逐渐从中部地区向东部、南部和北部地区传播。在2008年病例数高的地区,2009年报告的病例数有所下降。以5岁儿童居多,占93.86%。其中,3岁儿童占79.69%。1-2岁年龄组发生重症或死亡的风险高于其他年龄组。实验室确诊病例30 953例,其中EV71感染占50.81%,Cox A16感染占28.27%,其他肠道病毒感染占20.93%。结论近2年来,中国大陆手足口病发病率、EV71型感染重症病例和死亡病例均明显上升。,造成严重的疾病负担和公共卫生问题。在EV71病毒为主的地区,应及早采取有效的干预措施,加强重症病例的救治,以降低病死率。手足口病防治中仍存在的技术问题有待进一步研究。
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