Stability analysis for fractional differential equations of an HIV infection model with cure rate

Yongqi Liu, Jiandong Xiong, Chunhua Hu, Chunsong Wu
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引用次数: 7

Abstract

In this paper, we introduce a fractional differential HIV/AIDS infected model with Beddington-DeAngelis functional response rate. Moreover as for a feature, we consider cure rate of infected CD4 T cells. We show that the model introduced in this paper has nonnegative solutions which are all bounded. What is more, we also give a detailed analysis for the asymptotic stability of both the free equilibrium and the infected equilibrium. We have proven that if the basic reproduction number R0 is less than unity, then the disease-free equilibrium is locally asymptotically stable. If R0 is greater than unity, the infected equilibrium is locally asymptotically stable under some conditions.
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具有治愈率的HIV感染模型分数阶微分方程的稳定性分析
本文引入了一个具有Beddington-DeAngelis功能反应率的分数阶差分HIV/AIDS感染模型。此外,作为一个特征,我们考虑了感染CD4 T细胞的治愈率。我们证明了所引入的模型具有非负的全有界解。此外,我们还详细地分析了自由平衡点和受感染平衡点的渐近稳定性。证明了如果基本繁殖数R0小于1,则无病平衡是局部渐近稳定的。当R0大于1时,在某些条件下,感染平衡点是局部渐近稳定的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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