Prevalence and Associated Risk Factors of Vestibular Dysfunction in Females with Menopause

N. John, M. Abid, Farooq Islam, A. Raza, Gulraiz Inderyas, Faiza Asghar
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Abstract

Background: Hormonal changes during menopause affect the vestibular system by interfering with homeostasis and by disrupting the enzyme cycles and neurotransmitter function. It has been observed that females have a higher risk of falling and this may increase after menopause. Balance in women is significantly affected by menopause. Objective: To find the prevalence of vestibular dysfunction in menopausal females and to find the risk factors associated with vestibular dysfunction. Methods: The analytical cross-sectional study was conducted from May to October 2021, the data was collected from 385 women in district Jhelum who had menopause after the age of 45 years.  Non-probability convenient sampling was used to collect data. The Berg balance scale, activity-specific balance confidence scale, and a self-made questionnaire for risk factors were used in the study. Results: According to the activity-specific balance confidence scale, 24.4% of the population had high, 60.5% moderate, and 15.1% low physical functioning. A score of less than 67% indicated that 48.1% of patients had a risk for falls in the future. Berg balance scale showed that 6.8% of patients had a high, 22.9% medium, and 60.4% low risk of falling, a score less than 45 demonstrated that 55.8% had a higher fall risk. Diabetes, hypertension, heart disease, and smoking were all statistically significant risk factors for falls (p≤0.001). Conclusion: The current study concludes that there is a significant risk of developing vestibular dysfunction, with an increased risk of falls after menopause in females. Hearing loss is the most common risk factor while obesity also has a great impact on the vestibular system. But there is an increased chance of falls in participants with stroke and hypertension. 
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绝经期女性前庭功能障碍的患病率及相关危险因素
背景:绝经期间的激素变化通过干扰体内平衡和破坏酶周期和神经递质功能来影响前庭系统。据观察,女性摔倒的风险更高,绝经后这一风险可能会增加。女性的平衡受到更年期的显著影响。目的:了解绝经期女性前庭功能障碍的患病率及与前庭功能障碍相关的危险因素。方法:于2021年5月至10月进行横断面分析研究,收集Jhelum区45岁以上绝经妇女385例资料。采用非概率方便抽样法采集数据。本研究采用Berg平衡量表、特定运动平衡置信度量表和自制危险因素问卷。结果:根据活动特异性平衡置信度量表,24.4%的人身体功能高,60.5%的人身体功能中等,15.1%的人身体功能低。低于67%的分数表明48.1%的患者未来有跌倒的风险。Berg平衡量表显示,6.8%的患者跌倒风险为高,22.9%为中,60.4%为低,小于45分的患者跌倒风险较高。糖尿病、高血压、心脏病和吸烟都是有统计学意义的跌倒危险因素(p≤0.001)。结论:目前的研究得出结论,女性绝经后发生前庭功能障碍的风险显著增加,跌倒的风险增加。听力损失是最常见的危险因素,而肥胖对前庭系统也有很大的影响。但是中风和高血压患者摔倒的几率增加了。
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