Segmentation of nuclei in digital pathology images

P. Guo, A. Evans, P. Bhattacharya
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引用次数: 16

Abstract

There are challenges for image cancer nuclei segmentation in clinical decision support systems for brain tumor diagnosis. In this study, we propose a method for segmentation of cancer nuclei when such conflicts of cancer nuclei involve ‘omics’ indicative of brain tumors pathologically. To constrain the problem space in the region of color information (i.e. cancer nuclei), we begin by converting the images into the V component of HSV (Hue, Saturation, Value) using the level-set segmentation (VLS) in the training stage, follow by applying the sparsity representation (SR) in the test stage. Via the SR, the proposed VLS-SR would exhibits an improved capability of searching recursively for the optimal threshold level-set in the working subsets of the SR for image cancer nuclei segmentation.
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数字病理图像中核的分割
在脑肿瘤诊断的临床决策支持系统中,图像癌核分割存在挑战。在这项研究中,我们提出了一种分割癌核的方法,当这种癌核冲突涉及脑肿瘤病理指示的“组学”时。为了将问题空间限制在颜色信息(即癌核)区域,我们首先在训练阶段使用水平集分割(VLS)将图像转换为HSV (Hue, Saturation, Value)的V分量,然后在测试阶段应用稀疏表示(SR)。通过该算法,VLS-SR算法具有较强的递归搜索最优阈值水平集的能力,可用于图像癌核分割。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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