[An occurrence of a neurogenic sarcoma in an irradiated field following the combined surgical-radiologic treatment of a childhood adenosarcoma of the kidney].

Radiobiologia, radiotherapia Pub Date : 1990-01-01
H J Eberhardt, S Friedrich, T Herrmann, U Roy
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Abstract

Malignant neoplasias in childhood generally are an increased risk for the patient to fall ill with a second tumor. Second tumors in former irradiation field are seldom, but are acknowledged radiogenically if histology is different to that of the first tumor and a sufficiently long period is between the two tumors. A patient is represented who had been operated and irradiated because of an adenosarcoma of the kidney at the age of seven and who has fallen ill with a neurogenic sarcoma in irradiation area more than 30 years later. The same patient had to suffer from radiogenic retardation during differentiation of lumbar apparatus of attitude and locomotion and on the other hand he became father of a healthy daughter at the age of 32.

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[儿童肾脏腺肉瘤手术-放射联合治疗后,在辐照场发生神经源性肉瘤]。
儿童时期的恶性肿瘤通常会增加患者患第二肿瘤的风险。第二次肿瘤很少出现在原照射区,但如果组织学与第一次肿瘤不同,且两次肿瘤之间有足够长的时间间隔,则可在放射学上得到确认。本案例中有一位患者在7岁时因肾脏腺肉瘤而接受手术和放疗,30多年后因放疗区发生神经源性肉瘤而患病。同一患者在腰椎姿态和运动器官分化期间遭受放射性发育迟缓,另一方面他在32岁时成为一个健康女儿的父亲。
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