[High-frequency ventilation: side effects and dangers].

J L Theissen, K Redmann, P P Lunkenheimer, G Grosskopff, R E Zimmermann, P Lawin
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引用次数: 0

Abstract

Dangers of high-frequency ventilation result from the lack of a sensitive monitoring technique. Mucosal lesions of the trachea and the bronchi as well as cooling of the patient can be prevented by adequate humidification and heating of the gas flow. It is still controversial whether HFV leads to increased mucus production or secretolysis, and whether it prevents or promotes aspiration. The influence of mobilisation or immobilisation of a pulmonary focus on its recovery is not well understood. Interferences of HFV with the autonomic nervous system and endocrine system, like an increased release of PGI2, an antidiuretic and narcotic effect, with the coagulation system and the acid-base balance are inconsistent and therefore need particular clinical observation.

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【高频通气:副作用和危险】。
高频通气的危险源于缺乏灵敏的监测技术。气管和支气管的粘膜病变以及患者的冷却可以通过适当的加湿和加热气流来防止。目前仍有争议的是,HFV是否会导致粘液产生或分泌增加,以及它是否会阻止或促进误吸。活动或固定肺病灶对其恢复的影响尚不清楚。HFV对自主神经系统和内分泌系统的干扰,如PGI2释放增加,抗利尿和麻醉作用,与凝血系统和酸碱平衡不一致,因此需要特别的临床观察。
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