A first demonstration of audio-frequency optical coherence elastography of tissue

S. Adie, S. Alexandrov, J. Armstrong, B. Kennedy, D. Sampson
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Abstract

Optical elastography is aimed at using the visco-elastic properties of soft tissue as a contrast mechanism, and could be particularly suitable for high-resolution differentiation of tumour from surrounding normal tissue. We present a new approach to measure the effect of an applied stimulus in the kilohertz frequency range that is based on optical coherence tomography. We describe the approach and present the first in vivo optical coherence elastography measurements in human skin at audio excitation frequencies.
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组织的音频光学相干弹性成像的首次演示
光学弹性成像旨在利用软组织的粘弹性特性作为对比机制,特别适合于肿瘤与周围正常组织的高分辨率区分。我们提出了一种基于光学相干层析成像的新方法来测量在千赫兹频率范围内施加刺激的效果。我们描述了这种方法,并在音频激励频率下首次在人体皮肤中进行了体内光学相干弹性测量。
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