Segmentation and the development of the vertebrate nervous system.

Journal de physiologie Pub Date : 1990-01-01
R Keynes, G Cook, J Davies, A Lumsden, W Norris, C Stern
{"title":"Segmentation and the development of the vertebrate nervous system.","authors":"R Keynes,&nbsp;G Cook,&nbsp;J Davies,&nbsp;A Lumsden,&nbsp;W Norris,&nbsp;C Stern","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>1. Recent experiments on the development of neural segmentation in chick embryos are reviewed. 2. Segmentation of the spinal peripheral nerves is governed by a subdivision of the somite-derived sclerotome into anterior and posterior halves. Migrating neural crest cells and outgrowing motor axons are confined to the anterior sclerotome as a result, in part, of inhibitory interactions with posterior sclerotome cells. 3. The sclerotomal distribution of certain molecules known to influence growing nerve cells in vitro, namely laminin, fibronectin, N-CAM, N-Cadherin and J1/tenascin/cytotactin, suggest that these molecules play no critical role in determining the preference of nerve cells for anterior sclerotome. 4. Peanut agglutinin (PNA) recognises cell surface-associated components on posterior cells which, when incorporated into liposomes, cause the abrupt collapse of sensory growth cones in vitro. The PNA receptor(s) may be inhibitory for nerve cells in vivo. 5. The chick hindbrain epithelium is segmented early in its development. Each branchiomotor nucleus in the series of cranial nerves V, VII and IX derives from a pair of segments lying in register with an adjacent branchial arch. Neurogenesis of motor and reticular axons begins in alternate segments, suggesting parallels with insect pattern formation.</p>","PeriodicalId":14735,"journal":{"name":"Journal de physiologie","volume":"84 1","pages":"27-32"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal de physiologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

1. Recent experiments on the development of neural segmentation in chick embryos are reviewed. 2. Segmentation of the spinal peripheral nerves is governed by a subdivision of the somite-derived sclerotome into anterior and posterior halves. Migrating neural crest cells and outgrowing motor axons are confined to the anterior sclerotome as a result, in part, of inhibitory interactions with posterior sclerotome cells. 3. The sclerotomal distribution of certain molecules known to influence growing nerve cells in vitro, namely laminin, fibronectin, N-CAM, N-Cadherin and J1/tenascin/cytotactin, suggest that these molecules play no critical role in determining the preference of nerve cells for anterior sclerotome. 4. Peanut agglutinin (PNA) recognises cell surface-associated components on posterior cells which, when incorporated into liposomes, cause the abrupt collapse of sensory growth cones in vitro. The PNA receptor(s) may be inhibitory for nerve cells in vivo. 5. The chick hindbrain epithelium is segmented early in its development. Each branchiomotor nucleus in the series of cranial nerves V, VII and IX derives from a pair of segments lying in register with an adjacent branchial arch. Neurogenesis of motor and reticular axons begins in alternate segments, suggesting parallels with insect pattern formation.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
脊椎动物神经系统的分割与发育。
1. 综述了近年来在鸡胚神经分割发育方面的研究进展。2. 脊髓周围神经的分割是由somite衍生的硬核组分为前半部分和后半部分。迁移的神经嵴细胞和生长的运动轴突被限制在前部硬核组,部分原因是与后部硬核组细胞的抑制相互作用。3.某些已知影响体外神经细胞生长的分子,即层粘连蛋白、纤维连接蛋白、N-CAM、n -钙粘蛋白和J1/tenascin/ cytoectin,在巩膜层的分布表明,这些分子在决定神经细胞对前巩膜层的偏好方面没有关键作用。4. 花生凝集素(PNA)识别细胞表面相关成分后细胞,当纳入脂质体,导致感觉生长锥突然崩溃在体外。PNA受体在体内可能对神经细胞有抑制作用。5. 鸡后脑上皮在发育早期呈分节状。脑神经V、VII和IX系列中的每一个支运动核都起源于与相邻的鳃弓相连的一对节段。运动轴突和网状轴突的神经发生开始于交替的节段,表明与昆虫模式形成相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Control of the maturation and the survival of central noradrenergic neurons in culture. Expression of T-type calcium current precedes neurite extension in neuroblastoma cells. Synaptic formations and modulations of synaptic transmissions between identified cerebellar neurons in culture. Regulation of neurotransmitter synthesis: from neuron to gene. In vitro and in vivo regulation of the expression of the tyrosine hydroxylase gene.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1