Effect of Silver Nanoparticles, Zinc Oxide Nanoparticles and Titanium Dioxide Nanoparticles on Microshear Bond Strength to Enamel and Dentin.

Z. Jowkar, N. Farpour, F. Koohpeima, M. Mokhtari, F. Shafiei
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引用次数: 15

Abstract

AIM This study was aimed to evaluate whether antibacterial pretreatment of enamel and dentin with silver nanoparticles (SNPs), zinc oxide nanoparticles (ZNPs) and titanium dioxide nanoparticles (TNPs) has any effect on the microshear bond strength of an etch-and-rinse adhesive system. MATERIALS AND METHODS Eighty human third molars were randomly assigned to eight subgroups (n = 10). Enamel groups included no pretreatment (E), pretreatments with SNPs (ESNP), ZNPs (EZNP) and TNPs (ETNP) before acid etching and adhesive application. Dentinal groups included no pretreat-ment (D), pretreatments with SNPs (DSNP), ZNPs (DZNP) and TNPs (DTNP). The specimens were bonded by Adper Single Bond and polyvinyl chloride microtubes and were restored with Z250 composite. The bonded surfaces underwent microshear bond strength (uSBS) test. Data in megapascal (MPa) were analyzed with the Kruskal-Wallis test and the Mann-Whitney test (p = 0.05). RESULTS There was not a significant difference among the groups in enamel (p > 0.05). There was no significant difference between the application of three nanoparticles and the control group in dentin. However, DSNPs had a higher uSBS (25.60 ± 14.61) than that of the DZNPs and DTNPs groups (p = 0.03 and p = 0.001, respectively). Also, the mean uSBS value was lower in dentin groups compared to the respective enamel groups (p < 0.05) except for groups DSNPs and ESNPs in which no significant difference was found (p > 0.05). CONCLUSION Pretreatment with SNPs, TNPs, and ZNPs can be suggested to achieve potent antibacterial activities without compromising the bond strength. The best result was obtained for pretreatment with SNPs compared to pretreatment with TNPs or ZNPs in dentin and enamel, albeit the differences were not significant in the enamel groups. CLINICAL SIGNIFICANCE Effective antibacterial treatment prior to adhesive bonding application is desirable to provide successful restoration if it would not adversely affect the bond strength of the adhesive system. Nanoparticles can be applied to meet this goal.
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纳米银、纳米氧化锌和纳米二氧化钛对牙本质和牙釉质微剪切结合强度的影响。
本研究旨在评价纳米银(SNPs)、氧化锌纳米粒子(ZNPs)和二氧化钛纳米粒子(TNPs)对牙釉质和牙本质的抗菌预处理是否对蚀刻-冲洗胶粘剂体系的微剪切结合强度有影响。材料与方法将80颗人第三磨牙随机分为8个亚组(n = 10)。牙釉质组包括未预处理组(E)、酸蚀前预处理组(ESNP)、znp前预处理组(EZNP)和TNPs前预处理组(ETNP)。牙体组包括未预处理组(D)、snp预处理组(DSNP)、znp预处理组(DZNP)和TNPs预处理组(DTNP)。采用Adper单键和聚氯乙烯微管进行粘接,并用Z250复合材料进行修复。结合表面进行了微剪切结合强度(uSBS)测试。megapascal (MPa)数据采用Kruskal-Wallis检验和Mann-Whitney检验进行分析(p = 0.05)。结果各组间牙釉质差异无统计学意义(p > 0.05)。三种纳米颗粒在牙本质上的应用与对照组无显著差异。DSNPs组的uSBS(25.60±14.61)高于DZNPs组和DTNPs组(p = 0.03和p = 0.001)。牙本质组的uSBS平均值低于牙釉质组(p < 0.05),但DSNPs组和ESNPs组间差异无统计学意义(p > 0.05)。结论SNPs、TNPs和ZNPs预处理可以在不影响结合强度的情况下获得较强的抗菌活性。与牙本质和牙釉质中TNPs或ZNPs预处理相比,SNPs预处理的效果最好,但牙釉质组间差异不显著。临床意义如果不影响粘接系统的粘接强度,在粘接应用前进行有效的抗菌治疗是提供成功修复的必要条件。纳米颗粒可以用于实现这一目标。
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