Integrating protein visualisation in the classroom with StarBiochem

Ceraj Ivica, Justin T. Riley, Charles Shubert, Lourdes M. Aleman, M. Kosinski-Collins, M. Rokop, K. Vandiver
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Abstract

Teaching about proteins, how their structure is specified and how in turn this influences their function has become an integral curriculum component for both introductory biology and biochemistry undergraduate courses. To understand how proteins work, students first learn about protein structure and its relationship to protein function. StarBiochem is a protein visualisation tool that is used to assist in teaching key structural biology concepts in an interactive manner. StarBiochem allows for the visualisation and manipulation of protein data bank (PBD) molecules in a 3D environment. In this manuscript, we provide examples of StarBiochem usage within high school and undergraduate curricula. Specifically, we will highlight how StarBiochem is currently used in undergraduate courses at the Massachusetts Institute of Technology (MIT), Brandeis University, and in high school outreach programs at the Broad Institute of Harvard and MIT and at the MIT Museum.
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将StarBiochem与课堂上的蛋白质可视化相结合
关于蛋白质的教学,它们的结构是如何被指定的,以及如何反过来影响它们的功能,已经成为生物学入门和生物化学本科课程中不可或缺的课程组成部分。为了理解蛋白质是如何工作的,学生们首先要学习蛋白质的结构及其与蛋白质功能的关系。StarBiochem是一种蛋白质可视化工具,用于以交互式方式辅助教学关键结构生物学概念。StarBiochem允许在3D环境中可视化和操纵蛋白质数据库(PBD)分子。在这份手稿中,我们提供了StarBiochem在高中和本科课程中使用的例子。具体来说,我们将重点介绍StarBiochem目前如何在麻省理工学院(MIT)、布兰代斯大学的本科课程中使用,以及在哈佛大学和麻省理工学院的布罗德研究所和麻省理工学院博物馆的高中推广项目中使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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