3D Bioprinting Applications as New Technology for Nerve Regeneration

A. Abdolmaleki, Aida Karimian, A. Asadi, Hussein A. Ghanimi
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Abstract

: The regeneration of nerve defects and nerve damage is considered as most difficult clinical issue worldwide. Current treatments for regenerating nerves following trauma restrict nerve recovery because of intricate neural structures and some inhibitory factors at the injured site. Researchers have constructed innovative three-dimensional (3D) scaffolds with complicated structures using bioprinting to overcome nerve tissue regeneration difficulties. The therapeutic potential of this method for application to both the central and peripheral nervous systems was assessed. This study provides an overview of recent advancements in 3D bioprinting development and their medicinal potential for the nervous system.
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生物3D打印作为神经再生新技术的应用
神经缺损和神经损伤的再生一直是世界范围内最困难的临床问题。由于复杂的神经结构和损伤部位的一些抑制因子,目前创伤后神经再生的治疗限制了神经的恢复。研究人员利用生物打印技术构建了具有复杂结构的创新型三维(3D)支架,以克服神经组织再生的困难。评估了该方法应用于中枢和周围神经系统的治疗潜力。本研究概述了3D生物打印技术的最新进展及其在神经系统方面的医学潜力。
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