[Differential diagnosis of allergic and non-allergic dermatitis by measuring the levels of acid phosphatase in neutrophils and peripheral blood lymphocytes].

Abstract

Using the cytoenzymatic method acid phosphatase was determined in peripheral blood neutrophils and lymphocytes in 25 patients with allergic eczema, 31 patients with eczema due to irritants and 18 clinically healthy subjects. In patients with allergic eczema the percent of neutrophils and lymphocytes containing acid phosphatase was decreased and the activity of this enzyme in neutrophils was reduced. In patients with non allergic eczema these values were normal. The method of determination of acid phosphate in neutrophils and lymphocytes is regarded as useful for the differentiation between both types of eczema.