Some Haematological Parameters of the Elderly in Sokoto, Nigeria

Amilo Gi
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Abstract

The assessment of haematological parameters is very necessary because, they are important proxy indicators useful in the assessment of immune status, therapeutic purposes and monitoring of disease progression and treatment outcome for proper patient management. This study was aimed at determining some haematological parameters in apparently healthy elderly persons living in Sokoto, Nigeria. This was a cross-sectional study involving a total of 105 apparently healthy elderly persons living in Sokoto. Elderly persons aged 60years and above were recruited for the study. Full blood counts (FBC) were determined using five part haematological analyser by Mindray, Germany. Data were analysed using Statistical Package of Social Sciences (SPSS) version 25. Haematological parameters showed distinct differences with some local reference ranges. This study found out that the values of WBC, Lymphocyte, Neutrophil, Eosinophil, Monocyte, RDW-CV, Platelet Count, MPV, PDW and Plateletcrit were within the normal range in according to reference ranges used in Sokoto. While the values of RBC, HCT, MCHC, MCH and MCV were lower based on reference values used in Sokoto. However, RDW-CV was raised. There were statistical significant increases in mean values of Hb, HCT and MCV among male than females in Sokoto metropolis (p<0.05). There was statistical significant increases in mean values of PLT count among females than males in (p<0.05). There were statistical differences in mean values of Neutrophil, RBC, HCT, PLT and PCT among different age groups in Sokoto metropolis (p<0.05). There were statistical differences in mean values of WBC, Lymphocyte, Neutrophil, Eosinophil, RDW-CV, PLT, PDW and PCT among different groups of BMI in Sokoto metropolis (p<0.05). It was observed that monocyte increased significantly with BMI from normal weight to obesity (p<0.05). In conclusion, this study established a baseline data for FBC in elderly in Sokoto. Some of the parameters under study vary with local reference range. Elderly have lower haemoglobin and HCT. There is age, gender and BMI variation in the parameters studied. There is need to establish a different reference ranges for elderly in a given location for proper understanding and management of elderly population in our society.
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尼日利亚索科托老年人的一些血液学参数
血液学参数的评估是非常必要的,因为它们是评估免疫状态、治疗目的和监测疾病进展和治疗结果的重要代理指标,有助于适当的患者管理。本研究旨在确定尼日利亚索科托看似健康的老年人的一些血液学参数。这是一项横断面研究,共涉及住在索科托的105名表面上健康的老年人。研究招募了60岁及以上的老年人。全血细胞计数(FBC)采用德国迈瑞公司的五部分血液学分析仪测定。数据分析使用社会科学统计软件包(SPSS)第25版。血液学参数与一些地方参考范围有明显差异。本研究根据Sokoto的参考范围,发现WBC、淋巴细胞、中性粒细胞、嗜酸性粒细胞、单核细胞、RDW-CV、血小板计数、MPV、PDW和血小板计数均在正常范围内。而RBC、HCT、MCHC、MCH和MCV的值低于Sokoto的参考值。然而,RDW-CV被提高了。索科托城区男性Hb、HCT、MCV均值高于女性,差异有统计学意义(p<0.05)。女性患者PLT计数平均值明显高于男性患者(p<0.05)。索科托市各年龄组中性粒细胞、红细胞、HCT、PLT、PCT均值比较,差异均有统计学意义(p<0.05)。索科托市各BMI组间WBC、淋巴细胞、中性粒细胞、嗜酸性粒细胞、RDW-CV、PLT、PDW、PCT均值比较,差异均有统计学意义(p<0.05)。从正常体重到肥胖,随着BMI的增加,单核细胞明显增加(p<0.05)。总之,本研究建立了索科托老年人FBC的基线数据。所研究的一些参数随当地参考范围而变化。老年人血红蛋白和HCT较低。研究参数中存在年龄、性别和BMI的差异。为正确认识和管理我们社会的老年人口,有必要为特定地区的老年人建立不同的参考范围。
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